Hemoglobin-Based Oxygen Carriers: Biochemical, Biophysical Differences, and Safety

Hemoglobin-based oxygen carriers (HBOCs) have been developed for decades as alternatives to red blood cell transfusion, but none is licensed in the US. Earlier products ran into safety problems. This CME activity is based on a commentary in Transfusion. It compares HBOCs from the first generation to the newest, and links their biochemical and biophysical properties to the safety problems seen in clinical trials. It also considers how to manage those risks when blood is unavailable, and how newer products are being designed to avoid them.

Target Audience

Healthcare Professionals 

Learning Objectives

  • Explore the biochemical, biophysical, and safety characteristics of Hemoglobin-Based Oxygen Carriers

Activity Disclosure

No commercial support has been accepted related to the development or publication of this activity.

This activity underwent peer review in line with the standards of editorial integrity and publication ethics. Conflicts of interest have been identified and resolved in accordance with John Wiley and Sons, Inc.’s Policy on Activity Disclosure and Conflict of Interest.

Course summary

Available credit: 
  • 1.00 AMA PRA Category 1 Credit(s)™
Course opens: 
02/26/2025
Course expires: 
02/25/2028
Cost:
$0.00

Article Authors

Jahr JS, MacKinnon K, Baum VC, and Alayash A

CME Editor

 

Julie Katz Karp MD

Julie Katz Karp MD

Julie Katz Karp MD has nothing to disclose.

 

John Wiley & Sons, Inc. is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians and approved by the American Board of Pathology (ABPath) for Continuing Certification (CC) formerly MOC.

John Wiley and Sons, Inc. designates this journal-based CME activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity. For information on applicability and acceptance of continuing medical education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within 1 hour. To successfully earn credit, participants must complete the activity during the valid credit period, which is up to three years from initial publication. Additionally, up to 3 attempts and a score of 70% or better is needed to pass the post test and claim CC credit. [ACGME competency/CC category: Medical Knowledge].

Available Credit

  • 1.00 AMA PRA Category 1 Credit(s)™

Price

Cost:
$0.00
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