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ForwardConcurrent Neonatal Alloimmune Neutropenia and Thrombocytopenia: Prevalence, Antibody Specificity, and Intensity in a large Brazilian cohort
In this cross-sectional study, 10,000 umbilical cord blood samples were analyzed for platelet and neutrophil counts. Neonates with thrombocytopenia and neutropenia were selected. Genotyping for HPA, HNA, and HLA class I was performed in mother-infant pairs to assess incompatibilities. Maternal sera were tested for anti-HPA, anti-HNA, and anti-HLA antibodies.
Target Audience
Healthcare Professionals
Activity Disclosure
No commercial support has been accepted related to the development or publication of this activity.
CME Editor, Julie Katz Karp MD reported no conflicts of interest or financial relationships relevant to this article. This activity underwent peer review in line with the standards of editorial integrity and publication ethics. Conflicts of interest have been identified and resolved in accordance with John Wiley and Sons, Inc.’s Policy on Activity Disclosure and Conflict of Interest.
Learning Objectives
Explore the concurrent occurrence of and maternal antibodies implicated in Fetal/Neonatal Alloimmune Thrombocytopenia (FNAIT) and Neonatal Alloimmune Neutropenia (NAIN) in a large cohort of Brazilian newborns
Course summary
- 1.00 AMA PRA Category 1 Credit(s)™
John Wiley & Sons, Inc. is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
John Wiley and Sons, Inc. designates this journal-based CME activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity. For information on applicability and acceptance of continuing medical education credit for this activity, please consult your professional licensing board.
This activity is designed to be completed within 1 hour. To successfully earn credit, participants must complete the activity during the valid credit period, which is up to three years from initial publication. Additionally, up to 3 attempts and a score of 70% or better is needed to pass the post test and claim CC credit. [ACGME competency/CC category: Medical Knowledge].
Available Credit
- 1.00 AMA PRA Category 1 Credit(s)™