Clot contraction of whole blood diminishes during storage and can be restored by adding platelets

The contraction of blood clots is a dramatic platelet-dependent process that minimizes the impact of thrombosis and supports the closure of lacerations. Whole blood (WB) stored up to 35 days is increasingly used to treat hemorrhagic shock, but the clot contractibility of this stored blood is unknown. We hypothesized that clot contractibility decreases during storage but can be restored by adding platelets.
Target Audience
Healthcare Professionals
Learning Objectives
Explore how clot contractibility changes in whole blood during storage
Activity Disclosure
No commercial support has been accepted related to the development or publication of this activity.
CME Editor, Julie Katz Karp MD reported no conflicts of interest or financial relationships relevant to this article. This activity underwent peer review in line with the standards of editorial integrity and publication ethics. Conflicts of interest have been identified and resolved in accordance with John Wiley and Sons, Inc.’s Policy on Activity Disclosure and Conflict of Interest.
Course summary
- 1.00 AMA PRA Category 1 Credit(s)™
John Wiley & Sons, Inc. is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
John Wiley and Sons, Inc. designates this journal-based CME activity for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity. For information on applicability and acceptance of continuing medical education credit for this activity, please consult your professional licensing board.
This activity is designed to be completed within 1 hour. To successfully earn credit, participants must complete the activity during the valid credit period, which is up to three years from initial publication. Additionally, up to 3 attempts and a score of 70% or better is needed to pass the post test and claim CC credit. [ACGME competency/CC category: Medical Knowledge].
Available Credit
- 1.00 AMA PRA Category 1 Credit(s)™

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