Mastering COVID-19 — Harnessing Post-Exposure Prophylaxis for Primary Care Excellence

COVID-19 is still a heavy burden in the US. CDC estimates put hospitalizations at up to 540,000 and deaths at up to 63,000 for 2024–25. The virus keeps changing, fewer people are getting vaccinated, and immunity is waning. In this CME Bulletin, Benjamin Silverberg, MD, MSc, FAAFP, FCUCM, gives family physicians an up-to-date look at:
- the variants now circulating and how symptoms are changing
- why viral load matters
- how to use post-exposure prophylaxis (PEP) to protect high-risk patients
- current, emerging and investigational treatments, including remdesivir, pemivibart and ensitrelvir
Target Audience
Healthcare Professionals
Learning Objectives
- Gain insight into the current burden of COVID-19 and develop an enhanced understanding of evolving viral variants, changing symptom patterns, and the significance of viral load.
- Increase understanding of the clinical significance and implementation of PEP for COVID-19.
- Expand knowledge of current, emerging, and investigational COVID-19 treatment options.
Activity Disclosures
This educational activity is supported by an independent medical educational grant from Shionogi Inc.
Course summary
- 1.00 Enduring Materials, Self-Study AAFP Prescribed credit(s)
- 1.00 AMA PRA Category 1 Credit(s)™

Benjamin Silverberg, MD, MSc, FAAFP, FCUCM
Stanford University School of Medicine, Stanford, CA
Benjamin Silverberg, MD, MSc, FAAFP, FCUCM discloses the following: Professor Silverberg has served as a consultant and/or speaker for: Valneva for a presentation on travel medicine and infectious diseases at the AAFP’s FMX event and received educational grants from Valneva and Hologic for work on travel medicine and health surveys respectively. He is also Co-Editor of the Journal of American College Health. Received honorarium in relation to their participation.
All planners and reviewers involved in the development of this activity declared no relevant financial relationships with ineligible companies.
This activity underwent review in line with standards of editorial integrity and publication ethics. Potential conflicts of interest have been identified and resolved in accordance with John Wiley and Sons, Inc.’s Policy on Activity Disclosure and Conflict of Interest. The primary resolution method was review by an unconflicted expert. For information about the accreditation of this program, please contact [email protected].
John Wiley & Sons, Inc. is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
John Wiley and Sons, Inc. and the American Academy of Family Physicians (AAFP) designates this enduring CME activity for a maximum of 1.0 AMA PRA Category 1 Credit™ and/or 1.00 Enduring Materials, Self-Study AAFP Prescribed credit(s). Physicians should only claim credit commensurate with the extent of their participation in the activity. For information on applicability and acceptance of continuing medical education credit for this activity, please consult your professional licensing board.
Available Credit
- 1.00 Enduring Materials, Self-Study AAFP Prescribed credit(s)
- 1.00 AMA PRA Category 1 Credit(s)™

Facebook
X
LinkedIn
Forward